Questions and Controversies in Localized Head and Neck Cancer

Expert: Paolo Bossi, University of Brescia, ASST Spedali Civili, Brescia, Italy Questions: 1-Is there a role for induction chemotherapy for head and neck squamous cell carcinoma other than laryngeal preservation? 2-Could we use weekly cisplatin instead of high-dose three-weekly cisplatin concomitantly with radiotherapy? 3-Do you prefer cetuximab or carboplatin for chemoradiotherapy in patients ineligible for cisplatin? 4-What is the current role of positron emission tomography (PET) in patients with localized head and neck squamous cell carcinoma? 5-What’s the best option for induction chemotherapy in nasopharyngeal cancer (docetaxel-cisplatin-5FU or gemcitabine-cisplatin)?